Connectionists: New on the VVTNS YouTube channel - Convergent comodulation : Rules & influence on circuit output | Farzan Nadim, New Jersey Inst. of Tech.

[David Hansel]

[image: VVTNS.png]

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New on the VVTNS YouTube Channel
https://www.wwtns.online/past-seminars-2025-2026

*Convergent comodulation: Rules and influence on circuit output *

lecture delivered on January 28,  2026  by

Farzan Nadim New Jersey Institute of Technology


*Abstract: *Neural circuits are continuously under the influence of
multiple chemical neuromodulators. The prevalent view is that
neuromodulation increases the flexibility of circuit output. However,
different modulators can have overlapping cellular and subcellular targets,
and thus convergence and occlusion may limit the repertoire of possible
circuit states. We propose a complementary view that convergent
comodulation may result in a more consistent circuit activity that, with
increasing numbers of modulators, becomes less dependent on the specific
identity of the modulators involved. We examine this hypothesis in the
crustacean stomatogastric ganglion, where multiple excitatory neuropeptides
activate the same ionic current and have similar effects on synapses.

*About VVTNS : Launched as the World Wide  Theoretical Neuroscience Seminar
(WWTNS) in November 2020 and renamed in homage to Carl van Vreeswijk in
Memoriam (April 20, 2022), Speakers have the occasion to talk about
theoretical aspects of their work which cannot be discussed in a setting
where the majority of the audience consists of experimentalists. The
seminars, **held on Wednesdays at 11 am ET,**  are 45-50 min long followed
by a discussion. The talks are recorded with authorization of the speaker
and are available to everybody on our YouTube channel.*



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