Connectionists: World wide VVTNS series: Wednesday, May 8 at 11am (EDT), Douglas Zhou, Jiatong University| "Neuronal network reconstruction through causality measures"

[David Hansel]

[image: VVTNS.png]
https://www.wwtns.online - on twitter: wwtns at TheoreticalWide

You are cordially invited to the lecture  given by

Douglas Zhou

Jiatong University
on the topic of

"Neuronal network reconstruction through causality measures*"*

The lecture will be held on zoom on *May 8, 2024*, at *11:00 am EDT *

To receive the zoom link: https://www.wwtns.online/register-page


*Abstract:  *Understanding the causal connectivity within a network is
crucial for unraveling its functional dynamics. However，the inferred causal
connections are fundamentally influenced by the choice of causality measure
employed, which may not always align with the actual structural
connectivity of the network. The relationship between causal and structural
connectivity, especially how different causality measures affect the
inferred causal links, requires further exploration. In this talk, we
examine nonlinear networks characterized by pulse signal outputs, such as
spiking neural networks, using four prevalent causality measures:
time-delayed correlation coefficient, time-delayed mutual information,
Granger causality, and transfer entropy. We provide a theoretical analysis
of the interconnections among these measures when applied to pulse signals.
Utilizing both a simulated Hodgkin–Huxley network and an empirical mouse
brain network as case studies, we validate the quantitative relationships
between these causality measures. Our results show a strong correspondence
between the causal connectivity derived from any of these measures and the
actual structural connectivity, thereby establishing a direct linkage
between them. We highlight that structural connectivity in networks with
output pulse signals can be reconstructed on a pairwise basis, without
needing global information from all network nodes, effectively avoiding the
curse of dimensionality. Our approach offers a robust and practical
methodology for reconstructing networks based on pulse outputs.

*About VVTNS : Created as the World Wide Neuroscience Seminar (WWTNS) in
November 2020 and renamed in homage to Carl van Vreeswijk in Memoriam
(April 20, 2022), its aim is to be a platform to exchange ideas among
theoreticians. Speakers have the occasion to talk about theoretical aspects
of their work which cannot be discussed in a setting where the majority of
the audience consists of experimentalists. The seminars, **held on
Wednesdays at 11 am ET,**  are 45-50 min long followed by a discussion. The
talks are recorded with authorization of the speaker and are available to
everybody on our YouTube channel.*
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-- 
"В каждой шутке есть доля шутки"

'Life is good ..' (Carl van Vreeswijk, 1962-2022)
---------------------------------------
David Hansel
Directeur de Recherche  au CNRS
Co-Group leader
Cerebral Dynamics Plasticity and Learning lab., CNRS
45 rue des Saints Peres 75270 Paris Cedex 06
Tel (Cell):   +33 607508403 - Fax (33).1.49.27.90.62


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