Connectionists: World wide VVTNS series: Wednesday, April 3 at 11am (EDT), Manuel Beiran Columbia University | Prediction of neural activity in connectome-constrained recurrent networks

[David Hansel]

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[image: VVTNS.png]
https://www.wwtns.online - on twitter: wwtns at TheoreticalWide

You are cordially invited to the lecture  given by

Manuel Beiran

Columbia University
on the topic of

"Prediction of neural activity in connectome-constrained recurrent networks
*"*

The lecture will be held on zoom on *April 3, 2024*, at *11:00 am EDT *

To receive the zoom link: https://www.wwtns.online/register-page

*Abstract:  *In this talk, I will explain a theory of
connectome-constrained neural networks in which a “student” network is
trained to reproduce the activity of a ground-truth “teacher”, representing
a neural system for which a connectome is available. Unlike standard
paradigms with unconstrained connectivity, here both networks have the same
connectivity but they have different biophysical parameters, reflecting
uncertainty in neuronal and synaptic properties. We find that the
connectome is often insufficient to constrain the dynamics of networks that
perform a specific task, illustrating the difficulty of inferring function
from connectivity alone. However, recordings from a small subset of neurons
can remove this degeneracy, producing dynamics in the student that agree
with the teacher. Our theory can prioritize which neurons to record from to
most efficiently unmeasured network activity. The analysis shows that the
solution spaces of connectome-constrained and unconstrained models are
qualitatively different, and provides a framework to determine when such
models yield consistent dynamics.

*About VVTNS : Created as the World Wide Neuroscience Seminar (WWTNS) in
November 2020 and renamed in homage to Carl van Vreeswijk in Memoriam
(April 20, 2022), its aim is to be a platform to exchange ideas among
theoreticians. Speakers have the occasion to talk about theoretical aspects
of their work which cannot be discussed in a setting where the majority of
the audience consists of experimentalists. The seminars, **held on
Wednesdays at 11 am ET,**  are 45-50 min long followed by a discussion. The
talks are recorded with authorization of the speaker and are available to
everybody on our YouTube channel.*
-- 
'Life is good ..' (Carl van Vreeswijk, 1962-2022)
---------------------------------------
David Hansel
Directeur de Recherche  au CNRS
Co-Group leader
Cerebral Dynamics Plasticity and Learning lab., CNRS
45 rue des Saints Pères 75270 Paris Cedex 06
Tel (Cell):   +33 607508403 - Fax (33).1.49.27.90.62

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