Connectionists: Computational Neuroscience Postdoc Positions

[Neymotin, Samuel (NKI)]

Postdoctoral scientist positions are available at the Nathan Kline Institute (NKI) for Psychiatric Research (https://www.nki.rfmh.org<https://www.nki.rfmh.org/>) to work on computational neuroscience research funded by recently awarded NIH and DoD grants.


Our NIH-funded projects investigate the brain's dynamic circuit motifs underlying internal vs. external-oriented processes in the auditory and interconnected areas, using circuit modeling of the thalamocortical system. In this project, the postdoc will build data-driven biophysical models constrained by data collected from electrophysiology labs at NKI and Columbia (Noelle O’Connell, Charlie Schroeder, Dan Javitt) & The Feinstein Institutes for Medical Research (Stephan Bickel), and then use the models to predict optimal neuromodulation strategies for inducing/suppressing circuit patterns, testable in vivo. Related projects include investigating the origin of electrophysiology patterns observed in the auditory system of animal models of schizophrenia (biomarkers including mismatch negativity and altered oscillatory patterns), and using modeling to predict their circuit-level origins and potential treatments. Recent related publications (https://www.biorxiv.org/content/10.1101/2022.02.03.479036v2.abstract , https://www.eneuro.org/content/9/4/ENEURO.0281-21.2022.abstract , https://www.sciencedirect.com/science/article/pii/S0006322319318517).


Our DoD project involves developing computational models of the hippocampal and entorhinal cortex circuitry used in spatial navigation, higher level decision making circuits, and integrating the models with agents learning to solve navigation tasks using neurobiologically-inspired learning rules. This project includes mathematicians and robotics researchers at UTK and CMU. Recent related publications (https://www.frontiersin.org/articles/10.3389/fncom.2022.1017284/full , https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0265808).


Applicants should have a strong background in: multiscale modeling using NEURON/NetPyNE, Python software development, neural/electrophysiology data analysis, machine learning, and writing/presenting research.


To apply, email a CV and cover letter to Sam Neymotin (samnemo at gmail.com). The position requires presence at NKI (New York), with part telecommuting.


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