Connectionists: Phd project in Brighton, UK, within SoCoBio's 4-year doctoral training program

[Sylvia Schröder]

Within SoCoBio‘s 4-year doctoral training program 
<https://southcoastbiosciencesdtp.ac.uk/>, the labs of Sylvia Schröde 
<https://www.sussex.ac.uk/research/labs/schroeder-lab/index>r 
<https://www.sussex.ac.uk/research/labs/schroeder-lab/index> and Leon 
Lagnado <https://lagnadolab.com/> are offering the following Phd project 
in collaboration with their industrial partner, Scientifica 
<https://www.scientifica.uk.com/>:

*“Integration of visual and behavioural signals in the early visual system”*

In this project, you will discover how *retinal, cortical and 
neuromodulatory inputs shape the responses of visual neurons* in the 
superior colliculus. The goal of your Phd project is to understand the 
*mechanisms of signal integration*, i.e. which inputs to the superior 
colliculus shape its neural activity, and the *advantages of this 
integration for visual processing*.

You will use *two-photon imaging*in awake mice to simultaneously record 
activity of neurons in the superior colliculus as well as of axons 
originating in the retina, visual cortex, or brainstem nuclei such as 
the dorsal raphe (serotonin). You will compare the responses of the 
axonal inputs to those in the neurons, and you will observe how these 
signals change depending on the visual input and the behaviour of the 
animal.

In the beginning of your project, you will *develop an advanced imaging 
technique in collaboration with our industrial partner, **Scientifica*. 
You will adapt the existing two-photon microscope to image two separate 
fields of view simultaneously.This technique, termed multi-region 
imaging, will enable you torecord inputs and outputs of superior 
colliculus at sufficient detail, speed, and quantity.

Application to the program: https://southcoastbiosciencesdtp.ac.uk/ 
<https://southcoastbiosciencesdtp.ac.uk/>

Project description: 
https://southcoastbiosciencesdtp.ac.uk/project/integration-of-visual-and-modulatory-inputs-in-the-early-visual-system/ 
<https://southcoastbiosciencesdtp.ac.uk/project/integration-of-visual-and-modulatory-inputs-in-the-early-visual-system/>

For further information, contact sylvia.schroeder at ucl.ac.uk 
<sylvia.schroeder at ucl.ac.uk>

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