Connectionists: postdoc position: registering fully reconstructed neurons to brain atlases
Rembrandt Bakker
r.bakker at donders.ru.nl
Thu Apr 30 03:51:40 EDT 2020
Postdoc position Neuroinformatics at Radboud University Nijmegen, The
Netherlands
This project 'NeuronsReunited' is about real, physical connections at
the most detailed level, where long-range axons that reach across the
brain target specific neurons in multiple brain areas/layers. Reliable
techniques to fully reconstruct such axons have only recently become
available. Our experimental partner (Clasca, Madrid) has been pioneering
with this and his lab is tracing neurons one by one at a high level of
precision. Several large projects are underway to map much larger
numbers of neurons (MouseLight, Allen Brain Cell Types), and the goal of
this project is to asses the precision of those large scale projects by
comparison with the "gold standard' neurons used in this project.
Deliverables of the project include tools for speeding up the conversion
of experimental data into digital axons, and to precisely place neurons
into a digital reference brain to reveal their context. They are applied
to existing and new data in mouse, and the resulting insights are
incorporated into new models for brain function.
The project is a collaboration between five international partners, two
experimental partners (Prof. Francisco Clasca, Madrid; Prof. Egidio
d’Angelo, Pavia) and three computational/theoretical partners (Prof.
Paul Tiesinga, Dr. Rembrandt Bakker, Nijmegen; Prof. Michele Giugliano,
Trieste; Prof. Sacha Van Albada, Jülich).
See the full job description and application form at
https://www.academictransfer.com/nl/291439/postdoctoral-researcher-neuroinformatics/
Best regards,
Rembrandt Bakker
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