Connectionists: postdoc position: registering fully reconstructed neurons to brain atlases

Rembrandt Bakker r.bakker at donders.ru.nl
Thu Apr 30 03:51:40 EDT 2020


Postdoc position Neuroinformatics at Radboud University Nijmegen, The 
Netherlands

This project 'NeuronsReunited' is about real, physical connections at 
the most detailed level, where long-range axons that reach across the 
brain target specific neurons in multiple brain areas/layers. Reliable 
techniques to fully reconstruct such axons have only recently become 
available. Our experimental partner (Clasca, Madrid) has been pioneering 
with this and his lab is tracing neurons one by one at a high level of 
precision. Several large projects are underway to map much larger 
numbers of neurons (MouseLight, Allen Brain Cell Types), and the goal of 
this project is to asses the precision of those large scale projects by 
comparison with the "gold standard' neurons used in this project.

Deliverables of the project include tools for speeding up the conversion 
of experimental data into digital axons, and to precisely place neurons 
into a digital reference brain to reveal their context. They are applied 
to existing and new data in mouse, and the resulting insights are 
incorporated into new models for brain function.

The project is a collaboration between five international partners, two 
experimental partners (Prof. Francisco Clasca, Madrid; Prof. Egidio 
d’Angelo, Pavia) and three computational/theoretical partners (Prof. 
Paul Tiesinga, Dr. Rembrandt Bakker, Nijmegen; Prof. Michele Giugliano, 
Trieste; Prof. Sacha Van Albada, Jülich).

See the full job description and application form at
https://www.academictransfer.com/nl/291439/postdoctoral-researcher-neuroinformatics/

Best regards,

Rembrandt Bakker
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