Models of LTP and LTD
Bill Skaggs
bill at nsma.arizona.edu
Tue Jun 6 06:52:25 EDT 2006
Here are a few things for you:
Zador A, Koch C, Brown TH: Biophysical model of a
Hebbian synapse. {\em Proc Nat Acad Sci USA} 1990, 87:6718-6722.
Proposes a specific, experimentally justified model of the dynamics of
LTP in hippocampal synapses.
Brown TH, Zador AM, Mainen ZF and Claiborne BJ (1991) Hebbian
modifications in hippocampal neurons, in ``Long-Term Potentiation: A
Debate of Current Issues'' (eds M Baudry and JL Davis) MIT Press,
Cambridge MS 357-389.
Summarizes the material in the previous paper, and explores the
consequences of the facts of LTP for the representations formed within
the hippocampus, using compartmental modeling techniques.
Holmes WR, Levy WB: Insights into associative long-term
potentiation from computational models of NMDA receptor-mediated
calcium influx and intracellular Calcium concentration changes. {\em
J Neurophysiol} 1990, 63:1148-1168.
Regards,
-- Bill
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