Connectionists: CFP: Probabilistic Modeling and Machine Learning in Structural and Systems Biology
Esa A Pitkanen
epitkane at cs.helsinki.fi
Fri Apr 7 08:04:27 EDT 2006
CALL FOR PAPERS
Workshop on
Probabilistic Modeling and Machine Learning
in Structural and Systems Biology
http://www.cs.helsinki.fi/group/bioinfo/events/pmsb06/
Tuusula, Finland, 17-18 June 2006
Deadline for submission: April 23, 2006
Motivation
The ever-ongoing growth in the amount of biological data, the
development of
genome-wide measurement technologies, and the shift from the study of
individual genes to systems view all contribute to the need to develop
computational techniques for learning models from data. At the same time,
the increase in available computational resources has enabled new, more
realistic modeling methods to be adopted.
In bioinformatics, most of the targets of interest deal with complex
structured objects: sequences, 2D and 3D structures or interaction
networks.
In many cases these structures are naturally described by probabilistic
graphical models, such as Hidden Markov Models, Conditional Random Fields
or Bayesian Networks. Recently, approaches that combine Support Vector
Machines and probabilistic models have been introduced (Fisher kernels,
Max-margin Markov Networks, Structured SVM). These techniques benefit from
efficient convex optimization approaches and thus are potentially
well-scalable to large problems in bioinformatics.
The increasing amount of high-throughput experimental data begins to
enable
the use of these advanced modelling methods in bioinformatics and systems
biology. At the same time new computational challenges emerge. Statistical
methods are required to process the data so that underlying potentially
complex statistical patterns can be discerned from spurious patterns
created by random effects. At its simplest this problem calls for data
normalization and statistical hypothesis testing, in the more general
case,
one is required to select a model (e.g. gene network) that best explains
the
data.
Objective
The aim of this workshop is to provide a broad look at the state of the
art
in the probabilistic modeling and machine learning methods involving
biological structures and systems, and to bring together method developers
and experimentalists working with the problems.
We encourage submissions bringing forward methods for discovering complex
structures (e.g. interaction networks, molecule/cellular structures) and
methods supporting genome-wide data analysis.
A non-exhaustive list of topics suitable of this workshop:
Methods
* Algorithms
* Bayesian Methods
* Data integration/fusion
* Feature/subspace selection
* High-throughput methods
* Kernel Methods
* Machine Learning
* Probabilistic Inference
* Structured output prediction
Applications
* Sequence Annotation
* Gene Expression
* Gene Networks
* Gene Prediction
* Metabolic Profiling
* Metabolic Reconstruction
* Protein Structure Prediction
* Protein Function Prediction
* Protein-protein interaction networks
The workshop is organized by the European Network of Excellence PASCAL
(Pattern Analysis, Statistical Modelling and Computational Learning) and
belongs to the thematic programme on 'Learning with Complex and Structured
Outputs'.
The workshop is immediately followed by the International Specialised
Symposium on Yeasts (ISSY25, June 18-21 2006) that has the theme 'Systems
biology of Yeast - From Models to Applications'.
Submissions
We invite to submit an extended abstract of maximum four pages, formatted
according to the Springer Lecture Notes in Computer Science style, to
the email address juho.rousu at cs.helsinki.fi
Selected papers from the workshop will be published in BMC Bioinformatics
special issue. BMC Bioinformatics has impact factor 5.42, which makes it
the
second highest ranked bioinformatics journal.
Important dates
* April 23, 2006: Abstract submission deadline
* May 7, 2006: Notification of acceptance
* May 31, 2006: Final version due
* June 17-18, 2006: Workshop
Invited Speakers (confirmed)
* Tommi Jaakkola, MIT
* Koji Tsuda, CBRC / AIST, Japan
Organizing Committee
* Florence d'Alché-Buc, Université d'Evry-Val d'Essonne
* Jaakko Astola, Tampere University of Technology
* Nello Cristianini, UC Davis / University of Bristol
* Liisa Holm, University of Helsinki
* Mark Girolami, University of Glasgow
* Samuel Kaski, Helsinki University of Technology
* Matej Oresic, Technical Research Centre of Finland
* Juho Rousu, University of Helsinki
* Esko Ukkonen, Helsinki Institute for Information Technology
* Jean-Philippe Vert, Ecole des Mines de Paris
Local Organization
* Juho Rousu, University of Helsinki
* Samuel Kaski, Helsinki University of Technology
* Esko Ukkonen, Helsinki Institute for Information Technology
* Esa Pitkänen, University of Helsinki, workshop secretary
Location
* The workshop will be held in Conference Hotel Gustavelund, 15 minute
trip from Helsinki-Vantaa airport.
-------------- next part --------------
CALL FOR PAPERS
Workshop on
Probabilistic Modeling and Machine Learning
in Structural and Systems Biology
http://www.cs.helsinki.fi/group/bioinfo/events/pmsb06/
Tuusula, Finland, 17-18 June 2006
Motivation
The ever-ongoing growth in the amount of biological data, the development of
genome-wide measurement technologies, and the shift from the study of
individual genes to systems view all contribute to the need to develop
computational techniques for learning models from data. At the same time,
the increase in available computational resources has enabled new, more
realistic modeling methods to be adopted.
In bioinformatics, most of the targets of interest deal with complex
structured objects: sequences, 2D and 3D structures or interaction networks.
In many cases these structures are naturally described by probabilistic
graphical models, such as Hidden Markov Models, Conditional Random Fields
or Bayesian Networks. Recently, approaches that combine Support Vector
Machines and probabilistic models have been introduced (Fisher kernels,
Max-margin Markov Networks, Structured SVM). These techniques benefit from
efficient convex optimization approaches and thus are potentially
well-scalable to large problems in bioinformatics.
The increasing amount of high-throughput experimental data begins to enable
the use of these advanced modelling methods in bioinformatics and systems
biology. At the same time new computational challenges emerge. Statistical
methods are required to process the data so that underlying potentially
complex statistical patterns can be discerned from spurious patterns
created by random effects. At its simplest this problem calls for data
normalization and statistical hypothesis testing, in the more general case,
one is required to select a model (e.g. gene network) that best explains the
data.
Objective
The aim of this workshop is to provide a broad look at the state of the art
in the probabilistic modeling and machine learning methods involving
biological structures and systems, and to bring together method developers
and experimentalists working with the problems.
We encourage submissions bringing forward methods for discovering complex
structures (e.g. interaction networks, molecule/cellular structures) and
methods supporting genome-wide data analysis.
A non-exhaustive list of topics suitable of this workshop:
Methods
* Algorithms
* Bayesian Methods
* Data integration/fusion
* Feature/subspace selection
* High-throughput methods
* Kernel Methods
* Machine Learning
* Probabilistic Inference
* Structured output prediction
Applications
* Sequence Annotation
* Gene Expression
* Gene Networks
* Gene Prediction
* Metabolic Profiling
* Metabolic Reconstruction
* Protein Structure Prediction
* Protein Function Prediction
* Protein-protein interaction networks
The workshop is organized by the European Network of Excellence PASCAL
(Pattern Analysis, Statistical Modelling and Computational Learning) and
belongs to the thematic programme on 'Learning with Complex and Structured
Outputs'.
The workshop is immediately followed by the International Specialised
Symposium on Yeasts (ISSY25, June 18-21 2006) that has the theme 'Systems
biology of Yeast - From Models to Applications'.
Submissions
We invite to submit an extended abstract of maximum four pages, formatted
according to the Springer Lecture Notes in Computer Science style, to
the email address juho.rousu at cs.helsinki.fi
Selected papers from the workshop will be published in BMC Bioinformatics
special issue. BMC Bioinformatics has impact factor 5.42, which makes it the
second highest ranked bioinformatics journal.
Important dates
* April 23, 2006: Abstract submission deadline
* May 7, 2006: Notification of acceptance
* May 31, 2006: Final version due
* June 17-18, 2006: Workshop
Invited Speakers (confirmed)
* Tommi Jaakkola, MIT
* Koji Tsuda, CBRC / AIST, Japan
Organizing Committee
* Florence d'Alché-Buc, Université d'Evry-Val d'Essonne
* Jaakko Astola, Tampere University of Technology
* Nello Cristianini, UC Davis / University of Bristol
* Liisa Holm, University of Helsinki
* Mark Girolami, University of Glasgow
* Samuel Kaski, Helsinki University of Technology
* Matej Oresic, Technical Research Centre of Finland
* Juho Rousu, University of Helsinki
* Esko Ukkonen, Helsinki Institute for Information Technology
* Jean-Philippe Vert, Ecole des Mines de Paris
Local Organization
* Juho Rousu, University of Helsinki
* Samuel Kaski, Helsinki University of Technology
* Esko Ukkonen, Helsinki Institute for Information Technology
* Esa Pitkänen, University of Helsinki, workshop secretary
Location
* The workshop will be held in Conference Hotel Gustavelund, 15 minute
trip from Helsinki-Vantaa airport.
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