Postdoc: TRN Applications in Multi-Resolution Molecular Modeling

Willy Wriggers wriggers at scripps.edu
Wed Jan 17 23:17:27 EST 2001


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             Postdoctoral Positions: 
TRN Applications in Multi-Resolution Molecular Modeling 
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The Scripps Research Institute (La Jolla, California) and its
Computational Structural Biology Group in the Department of Molecular
Biology (http://www.scripps.edu/wriggers) are seeking highly qualified
Postdoctoral Research Associates to develop and apply multi-resolution
modeling techniques based on topology-representing networks (TRN) for
the determination of 3D atomic structures of proteins and large
biomolecular assemblies. 

Highly qualified applicants should hold a Ph.D. degree in physics,
chemistry, computer science, or a related quantitative discipline.
Research experience in image-processing, neural networks, or
visualization are an essential asset. We expect a strong programming
background, organizational skills, and a desire to learn principles
of structural biology.

The successful candidates may choose among the following research
topics:

- neural network-based shape characterization and query;
- shape-based docking of multi-resolution biomolecular data;
- flexible docking with force-field methods (molecular dynamics and 
  normal mode analysis);
- spline-based warping (morphing) of 3D structural data;
- interactive visualization (computer graphics) of atomic and 
  low-resolution data.

The developed algorithms will be applied in challenging collaborations
with world leaders in Electron Microscopy involving structures of virus
capsids, RNA polymerase, cytoskeletal filaments and the ribosome.

Initial appointments are for one year, but are extendable to the full
time frame of the projects (up to 5 years). Application review begins
immediately until the positions are filled. Ideally, candidates should
be able to start by April, 2001, although highly qualified candidates
who seek a later start date should not hesitate to apply. We offer a
competitive salary and benefits.

If you are interested in applying for a position, please email your CV,
a letter of application (research interests and publication list), and a
list of references (with name, email, and phone number) to me. There are
no citizenship restrictions. Qualified women and minority candidates are
encouraged to apply. TSRI is an Equal Opportunity employer.

Willy Wriggers
Assistant Professor
Department of Molecular Biology, TPC6
The Scripps Research Institute
10550 North Torrey Pines Road
La Jolla, California 92037
E-mail: wriggers at scripps.edu
URL: http://www.scripps.edu/wriggers
Tel: (858)784-8823
Fax: (858)784-8688




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