<div dir="ltr"><div class="gmail_quote gmail_quote_container"><br><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr" class="gmail_attr" style="text-align:center"><img src="cid:ii_l25sulo01" alt="VVTNS.png" width="236" height="236" style="margin-right: 0px;"></div><div dir="ltr" class="gmail_attr" style="text-align:center"><a href="https://streaklinks.com/A9c7PbbpKY7PxB6PaAJWGD3-/https%3A%2F%2Fwww.wwtns.online" style="font-size:large" target="_blank">https://www.wwtns.online</a><span style="font-size:large"> - on twitter: wwtns@TheoreticalWide</span></div><div dir="ltr" class="gmail_attr" style="text-align:center"><font size="4"><br></font></div><div dir="ltr" class="gmail_attr" style="text-align:center"><font size="4">You are cordially invited to </font><span style="font-size:large">the lecture </span></div><div dir="ltr" class="gmail_attr" style="text-align:center"><span style="font-size:large"><font color="#000000"><br></font></span></div><div class="gmail_attr" style="text-align:center"><p style="margin-bottom:0cm"><font size="4">Stefan Rotter</font></p><p style="vertical-align:baseline;background:0px 0px;border:0px;outline:0px;padding:0px;font-style:normal;font-variant:normal;font-size-adjust:none;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;line-height:1.6em;font-family:spinnaker,sans-serif;margin:0px">
</p><p style="margin-bottom:0cm"><font size="4">Bernstein Center Freiburg & Faculty
of Biology, University of Freiburg, Germany</font></p></div><div dir="ltr" class="gmail_attr" style="text-align:center"><br></div><div class="gmail_attr" style="text-align:center"><font color="#000000" style="background-color:transparent"> </font><span style="font-size:large;background-color:transparent;color:rgb(0,0,0)">on the topic of </span></div><div class="gmail_attr" style="text-align:center">
<h1 style="font-family:"Arial Narrow",sans-serif;font-size:18pt;margin-bottom:0.21cm"><span style="font-weight:normal">Emergent associative plasticity in neuronal
networks with limited synaptic resources</span></h1></div><div class="gmail_attr" style="text-align:center"><br></div><div class="gmail_attr" style="text-align:center"><br></div><div dir="ltr" class="gmail_attr" style="text-align:center"><font size="4">The lecture will be held on Zoom on June 3, 2026 at <u><b>11:00 am ET </b></u> </font> </div><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div 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receive the link: </span><a href="https://www.wwtns.online/register-page" target="_blank" style="font-size:large">https://www.wwtns.online/register-page</a><span style="color:rgb(0,0,0);font-size:large"> </span></p></div></div></div></div></blockquote><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div dir="ltr"><div class="gmail_quote"><div class="gmail_quote"><div dir="ltr"><p style="text-align:center;color:rgb(3,3,3);line-height:1em"><span style="color:rgb(0,0,0);font-size:large"> </span></p></div></div></div></div></blockquote><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div><font color="#000000"><span style="font-family:spinnaker,sans-serif;text-align:justify"><b><span style="font-size:14px">Abstract:</span> </b></span></font>Structural plasticity and other forms
of network remodeling are important and well-documented processes
during brain development, maturation, learning, and aging. Remarkably
high turnover rates in neural connectivity have been observed under
baseline conditions, and these rates increase even more significantly
in response to stimulation or perturbation. However, little is known
about the underlying molecular mechanisms and biological function of
this drastic form of brain plasticity. Since direct experiments on
connectivity at the synaptic level are notoriously difficult to
conduct and analyze, formal models are crucial for predicting and
understanding the emergent properties of networks (or graphs) with
highly dynamic structures. Building on our previous work on
homeostatic structural plasticity, we have developed a new model of
self-organizing networks based on the “directed configuration
model.” It exhibits Hebbian plasticity (“neurons that fire
together wire together”) and engram formation without specific
molecular mechanisms. I will also discuss possible connections with
psychological phenomena such as classical conditioning, extinction,
and blocking, and describe new machine learning strategies based on
self-organizing networks that can be derived from our biologically
motivated theory.</div>
<div><span style="font-family:spinnaker,sans-serif;font-size:14px;text-align:justify"><font color="#000000"><br></font></span></div><div><div><i style="background-color:transparent;color:rgb(80,0,80)"><font color="#000000"><span style="font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify"><b>About VVTNS :</b> Launched as the World Wide Theoretical Neuroscience Seminar (WWTN</span><span style="font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify">S) in N</span></font><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify">ovember 2020 and renamed in homage to Carl van Vreeswijk in Memoriam (April 20, 2022), Speakers have the occasion to talk about theoretical aspects of their work which cannot be discussed in a setting where the majority of the audience consists of experimentalists. The seminars, </span></i><i style="background-color:transparent;color:rgb(80,0,80)"><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify">held on Wednesdays at 11 am ET,</span></i><i style="background-color:transparent;color:rgb(80,0,80)"><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify"> are 45-50 min long followed by a discussion. The talks are recorded with authorization of the speaker and are available to everybody on our YouTube channel.</span></i><span style="color:rgb(0,0,0);font-family:spinnaker,sans-serif;font-size:14px;text-align:justify"></span></div><div><span style="color:rgb(0,0,0);font-family:spinnaker,sans-serif;font-size:14px;text-align:justify"><br></span></div><br></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>
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