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<div><span style="color: rgba(0, 0, 0, 0.847); font-family: Arial, Arial_EmbeddedFont, Arial_MSFontService, sans-serif; font-size: 11pt; white-space: pre-wrap; background-color: rgb(255, 255, 255); text-align: justify; orphans: 2; widows: 2;">Dear Colleagues,</span></div>
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<span data-contrast="auto" xml:lang="EN-GB" lang="EN-GB" class="TextRun SCXW215595721 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; font-size: 11pt; line-height: 17px; font-family: Arial, Arial_EmbeddedFont, Arial_MSFontService, sans-serif; font-variant-ligatures: none !important;">EBRAINS
is pleased to announce a call for contributions to the </span><span data-contrast="auto" xml:lang="EN-GB" lang="EN-GB" class="TextRun SCXW215595721 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; font-size: 11pt; font-style: italic; line-height: 17px; font-family: Arial, Arial_EmbeddedFont, Arial_MSFontService, sans-serif; font-variant-ligatures: none !important;">EBRAINS
10-Year Roadmap 2026–2036</span><span data-contrast="auto" xml:lang="EN-GB" lang="EN-GB" class="TextRun SCXW215595721 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px; font-size: 11pt; line-height: 17px; font-family: Arial, Arial_EmbeddedFont, Arial_MSFontService, sans-serif; font-variant-ligatures: none !important;"><span class="NormalTextRun SCXW215595721 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px;">.
This call is the first major step in a community-driven process that will define the scientific,
</span><span class="NormalTextRun SCXW215595721 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px;">clinical</span><span class="NormalTextRun SCXW215595721 BCX0" style="-webkit-user-drag: none; margin: 0px; padding: 0px;"> and technological priorities
guiding the evolution of EBRAINS as Europe’s digital research infrastructure for neuroscience. </span></span><span class="EOP SCXW215595721 BCX0" data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335551550":6,"335551620":6,"335559740":240}" style="-webkit-user-drag: none; margin: 0px; padding: 0px; font-size: 11pt; line-height: 17px; font-family: Arial, Arial_EmbeddedFont, Arial_MSFontService, sans-serif;"> </span></p>
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<span lang="EN-GB" style="font-family: Arial, sans-serif;">Purpose and Vision<o:p></o:p></span></h1>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">EBRAINS invites the neuroscience, clinical, and technology communities to co-create the <i>EBRAINS 10-year Roadmap 2026–</i>2036<b> </b>— a shared vision and implementation plan for
the next decade of digital neuroscience in Europe.<o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">This roadmap aims to identify the scientific, clinical, and technological priorities<b> </b>that will guide EBRAINS as a European research infrastructure.<o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">We seek visionary yet concrete proposals that define <u>science that cannot be done elsewhere</u> — projects, capabilities, or collaborations uniquely enabled by EBRAINS’ data, models,
compute, and federated ecosystem. <o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Proposed activities should make full use of the EBRAINS suite of digital tools and services.<o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">The call presentation by Prof. Viktor Jirsa, EBRAINS Chief Scientific Officer, will take place at the </span><span lang="EN-US"><a href="https://summit2025.ebrains.eu/programme" style="color: rgb(150, 96, 125);"><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">EBRAINS
Summit 2025 - Transforming Brain Research and Medicine</span></a></span><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"> on <b>December 10, 11h10–11h45 CET</b>. <o:p></o:p></span></p>
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<span lang="EN-GB" style="font-family: Arial, sans-serif;">Key actions and timeline<o:p></o:p></span></h1>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Official launch of the roadmap process at the EBRAINS Summit 2025<o:p></o:p></span></p>
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<b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">December 10, 2025<o:p></o:p></span></b></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Submission deadline for proposals<o:p></o:p></span></p>
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<b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">March 1, 2026</span></b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">EBRAINS Strategy Symposium<o:p></o:p></span></p>
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<b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Q2 2026</span></b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Publication of</span><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"> Roadmap Contributions</span><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
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<b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">April 15, </span></b><b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">2026</span></b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Synthesis into the EBRAINS 10-Year Roadmap (approximately 10 pages)<o:p></o:p></span></p>
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<b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Q4 2026</span></b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Adoption of the Roadmap by EBRAINS governance as EBRAINS’ official strategic framework<o:p></o:p></span></p>
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<b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">Q1 2027</span></b><span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;"> </span></p>
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<span lang="EN-GB" style="font-size: 11pt; font-family: Arial, sans-serif;">We are looking forward to your proposals and your participation to the call presentation at the <b>EBRAINS Summit</b>on <b>December 10, 11h10–11h45 CET</b>. Contributing to the <b>EBRAINS
10-year Roadmap </b>means taking part in defining the next decade of neuroscience - <b>not as an observer, but as an architect.</b><o:p></o:p></span></p>
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<b><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">Find out more</span></b><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;"> </span><span lang="EN-US"><a href="https://www.ebrains.eu/news-and-events/call-for-contributions-to-the-ebrains-10-year-roadmap-2026-2036" style="color: rgb(150, 96, 125);"><b><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">HERE</span></b></a></span><span lang="EN-US" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;"> </span><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">about
the purpose of EBRAINS 10-Year Roadmap, </span><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">who can contribute, format of contributions, </span><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">why
participate, review and integration process, review criteria.<o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">Kind regards, <o:p></o:p></span></p>
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<span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">Viktor Jirsa, Katrin Amunts, Philippe Vernier<o:p></o:p></span></p>
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<b><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">on behalf of the EBRAINS Management Board<o:p></o:p></span></b></p>
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<span lang="EN-US"><a href="mailto:ebrains-roadmap@ebrains.eu" style="color: rgb(150, 96, 125);"><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;">ebrains-roadmap@ebrains.eu</span></a></span><span lang="EN-GB" style="font-size: 11pt; line-height: 16.866667px; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
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