<div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr" class="gmail_attr"><br></div><br><br><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div 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href="https://streaklinks.com/A9c7PbbpKY7PxB6PaAJWGD3-/https%3A%2F%2Fwww.wwtns.online" style="font-size:large" target="_blank">https://www.wwtns.online</a><span style="font-size:large"> - on twitter: wwtns@TheoreticalWide</span></div><div dir="ltr" class="gmail_attr" style="text-align:center"><font size="4"><br></font></div><div dir="ltr" class="gmail_attr" style="text-align:center"><span style="color:rgb(0,0,0);font-family:arial,sans-serif;font-size:large">You are cordially invited to the lecture given by</span></div><div dir="ltr" class="gmail_attr" style="text-align:center"><span style="color:rgb(0,0,0);font-family:arial,sans-serif;font-size:large"><br></span></div><div class="gmail_attr" style="text-align:center"><font color="#000000" face="arial, sans-serif" size="4">Claire Meissner-Bernard</font></div><div class="gmail_attr" style="text-align:center"><span style="font-family:helvetica-w01-roman,helvetica-w02-roman,helvetica-lt-w10-roman,sans-serif;font-size:18px">Friedrich Miescher Institut </span><span style="font-family:helvetica-w01-roman,helvetica-w02-roman,helvetica-lt-w10-roman,sans-serif;font-size:18px">for biomedical research</span></div><div class="gmail_attr" style="text-align:center"><span style="font-family:helvetica-w01-roman,helvetica-w02-roman,helvetica-lt-w10-roman,sans-serif;font-size:18px">Basel</span></div><div class="gmail_attr" style="text-align:center"><span style="font-family:helvetica-w01-roman,helvetica-w02-roman,helvetica-lt-w10-roman,sans-serif;font-size:18px"><br></span></div><div dir="ltr" class="gmail_attr" style="text-align:center"><font color="#000000" style="background-color:transparent"> </font><span style="background-color:transparent;font-size:large;color:rgb(0,0,0)">on the topic of </span></div><div dir="ltr" class="gmail_attr" style="text-align:center"><font color="#000000"><br></font></div><div dir="ltr" class="gmail_attr" style="text-align:center"><p style="background:transparent;border:0px;outline:0px;padding:0px;vertical-align:baseline;line-height:normal;margin:0px"><font color="#000000"><span style="font-family:spinnaker,sans-serif"><span style="font-size:20px">Properties of memory networks with excitatory-inhibitory assemblies</span></span><span style="font-family:spinnaker,sans-serif"><span style="font-size:20px"></span></span><span style="font-family:spinnaker,sans-serif"><span style="font-size:20px"></span></span></font></p><p style="background:transparent;border:0px;outline:0px;padding:0px;vertical-align:baseline;font-size:20px;line-height:normal;margin:0px"><span style="background:transparent;border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline"><font color="#000000"><br></font></span></p></div><div dir="ltr" class="gmail_attr" style="text-align:center"><font size="4">The lecture will be held on zoom on Wednesday, December 18, 2024, at <u><b>11:00 am EST </b></u> </font> </div><div dir="ltr" class="gmail_attr" style="text-align:center"><span style="font-size:large"><br></span></div><div dir="ltr" class="gmail_attr" style="text-align:center"><span style="font-size:large">To receive the zoom link: </span><a href="https://www.wwtns.online/register-page" target="_blank" style="font-size:large">https://www.wwtns.online/register-page</a></div><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div 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dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div><font color="#000000"><font size="4" face="garamond, times new roman, serif"><b><br></b></font></font></div><div><font color="#000000"><font size="4" face="garamond, times new roman, serif"><b>Abstract: </b></font><span style="font-family:spinnaker,sans-serif;font-size:14px;text-align:justify"> </span><span style="font-family:spinnaker,sans-serif;letter-spacing:0em;font-size:14px">Classical views suggest that memories are stored in assemblies of excitatory neurons that become strongly interconnected during learning. However, recent experimental and theoretical results have challenged this view, leading to the hypothesis that memories are encoded in assemblies containing both excitatory (E) and inhibitory (I) neurons. Understanding the effects of these E-I assemblies on memory function is therefore essential. Using a biologically constrained model of an olfactory memory network, I will first describe how introducing E-I assemblies reorganizes odor-evoked activity patterns in neural state space. Indeed, the “geometry” of neural activity provides valuable insights about the computational properties of neural networks. I will then describe the behavior of networks with E-I assemblies upon partial manipulation of inhibitory neurons. Finally, I will discuss recent experimental data supporting predictions of the model.</span></font></div><div><font color="#000000"><span style="font-family:spinnaker,sans-serif;font-size:14px;text-align:justify"><br></span></font></div><div><i style="background-color:transparent;color:rgb(80,0,80)"><font color="#000000"><span style="font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify"><b>About VVTNS :</b> Launched as the World Wide Theoretical Neuroscience Seminar (WWTN</span><span style="font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify">S) in N</span></font><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify">ovember 2020 and renamed in homage to Carl van Vreeswijk in Memoriam (April 20, 2022), Speakers have the occasion to talk about theoretical aspects of their work which cannot be discussed in a setting where the majority of the audience consists of experimentalists. The seminars, </span></i><i style="background-color:transparent;color:rgb(80,0,80)"><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify">held on Wednesdays at 11 am ET,</span></i><i style="background-color:transparent;color:rgb(80,0,80)"><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify"> are 45-50 min long followed by a discussion. The talks are recorded with authorization of the speaker and are available to everybody on our YouTube channel.</span></i><span style="color:rgb(0,0,0);font-family:spinnaker,sans-serif;font-size:14px;text-align:justify"></span></div><div><span style="color:rgb(0,0,0);font-family:spinnaker,sans-serif;font-size:14px;text-align:justify"><br></span></div><div><span style="color:rgb(0,0,0);font-family:spinnaker,sans-serif;font-size:14px;text-align:justify"><br></span></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>
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