<div dir="ltr"><span style="margin:0px;padding:0px;border:0px;font-size:13px;font-family:Arial;vertical-align:baseline;color:rgb(37,44,47)"><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)">Are you passionate about advancing rehabilitation robotics? Do you want to help create predictive computer models that can reshape how we approach rehabilitation following severe neuro-muscular injuries via novel rehabilitation robots? </span></span><div><span style="margin:0px;padding:0px;border:0px;font-size:13px;font-family:Arial;vertical-align:baseline;color:rgb(37,44,47)"><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)"><br></span></span></div><div><span style="margin:0px;padding:0px;border:0px;font-size:13px;font-family:Arial;vertical-align:baseline;color:rgb(37,44,47)"><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)">Join us at the Neuro-Mechanical Modeling and Engineering Lab (<span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:blue"><u style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline"><a href="http://bit.ly/NMLab" target="_blank" style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(35,121,181);text-decoration:none">http://bit.ly/NMLab</a>),</u></span>where we're pushing boundaries in muscle neurophysiology, biomechanics, and robotics as part of the ERC Consolidator Grant ROBOREACTOR (<a href="https://cordis.europa.eu/project/id/101123866" target="_blank" style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(35,121,181);text-decoration:none">https://cordis.europa.eu/project/id/101123866</a>).</span><br><br><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)">This 4-year PhD position offers you the chance to work in an innovative interdisciplinary environment, collaborating on groundbreaking research at the frontier of healthcare and robotics (<a href="http://bit.ly/NMLTube" target="_blank" style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(35,121,181);text-decoration:none">http://bit.ly/NMLTube</a>).</span><br><br><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)"><b style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline"><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(54,95,145)">Project Overview</span></b></span><br><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)">As a PhD fellow, you’ll play a central role in building a predictive, multi-scale model of human skeletal muscle. This model will simulate how motor units within muscles respond to neural signals discharged by spinal neurons and adapt structurally over time when subjected to specific physical strain regimens. Leveraging machine learning and statistical modeling, you’ll integrate data from<span class="gmail-Apple-converted-space"> </span><i style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline">in vivo</i><span class="gmail-Apple-converted-space"> </span>and<span class="gmail-Apple-converted-space"> </span><i style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline">in vitro</i><span class="gmail-Apple-converted-space"> </span>studies to accurately predict muscle remodelling. The model will be validated against data from both healthy participants and post-stroke patients following a targeted 12-week leg training protocol. Using advanced tools such as high-density electromyography, ultrasound, and robotic dynamometry, you'll bridge biomechanics, neurophysiology and robotics, driving novel insights in muscle modelling and rehabilitation.</span><br><br><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)"><b style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline"><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(54,95,145)">Key Responsibilities</span></b></span><br><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)">As part of our team, you will:</span></span><ul style="margin:1em 1em 1em 2em;padding:0px;border:0px;font-size:13px;font-family:Helvetica,Arial,Verdana,sans-serif;vertical-align:baseline;list-style:none;color:rgb(37,44,47)"><li style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;list-style:outside"><span style="margin:0px;padding:0px;border:0px;font-family:Arial;vertical-align:baseline">Develop a computational muscle model, particularly for leg muscles, that simulates biological remodelling over time based on strain stimuli.</span></li><li style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;list-style:outside"><span style="margin:0px;padding:0px;border:0px;font-family:Arial;vertical-align:baseline">Use high-density EMG, ultrasound, and force dynamometry to personalize models to reflect individual neuromuscular physiology.</span></li><li style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;list-style:outside"><span style="margin:0px;padding:0px;border:0px;font-family:Arial;vertical-align:baseline">Program model remodelling logics in languages such as C++ and Python.</span></li><li style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;list-style:outside"><span style="margin:0px;padding:0px;border:0px;font-family:Arial;vertical-align:baseline">Train machine learning algorithms to identify the most probable muscle remodelling processes based on strain data.</span></li><li style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;list-style:outside"><span style="margin:0px;padding:0px;border:0px;font-family:Arial;vertical-align:baseline">Validate the model with both healthy and stroke patients, as well as through<span class="gmail-Apple-converted-space"> </span><i style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline">in vitro</i><span class="gmail-Apple-converted-space"> </span>muscle data.</span></li><li style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;list-style:outside"><span style="margin:0px;padding:0px;border:0px;font-family:Arial;vertical-align:baseline">Collaborate with experts in control engineering, robotics, and bioengineering to contribute to developing a rehabilitation robotic system capable of autonomous tissue regeneration.</span></li></ul><span style="margin:0px;padding:0px;border:0px;font-size:13px;font-family:Arial;vertical-align:baseline;color:rgb(37,44,47)"><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(0,0,0)"><b style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline"><span style="margin:0px;padding:0px;border:0px;font-family:inherit;vertical-align:baseline;color:rgb(54,95,145)">Key Responsibilities</span></b><br><b>Apply by November 28th following the instructions outlined at this link:<span class="gmail-Apple-converted-space"> </span></b></span></span><b><a href="https://t.co/brbfHEKPiX" target="_blank" style="margin:0px;padding:0px;border:0px;font-size:13px;font-family:Helvetica,Arial,Verdana,sans-serif;vertical-align:baseline;color:rgb(35,121,181);text-decoration:none">https://bit.ly/3AD3CDC</a><a href="https://bit.ly/3AD3CDC" target="_blank" style="margin:0px;padding:0px;border:0px;font-size:13px;font-family:Helvetica,Arial,Verdana,sans-serif;vertical-align:baseline;color:rgb(35,121,181);text-decoration:none"></a></b><br></div><div><br></div><div><p class="MsoNormal" style="margin:0cm;font-size:11pt;font-family:Aptos,sans-serif;color:rgb(0,0,0)"><span style="font-family:Calibri,sans-serif">---<br>Massimo Sartori<br>Full Professor and Head of Chair, Neuromuscular Robotics</span></p><p class="MsoNormal" style="margin:0cm;font-size:11pt;font-family:Aptos,sans-serif;color:rgb(0,0,0)"><span style="font-family:Calibri,sans-serif">Lab Head, Neuromechanical Modeling and Engineering Lab<br></span><span style="font-size:5pt;font-family:Calibri,sans-serif"> <br></span><span style="font-family:Calibri,sans-serif">University of Twente</span><span lang="EN-US" style="font-family:Calibri,sans-serif">,<span class="gmail-Apple-converted-space"> </span></span><span style="font-family:Calibri,sans-serif">TechMed Centre</span><span lang="EN-US" style="font-family:Calibri,sans-serif">, Robotics Centre</span><span style="font-family:Calibri,sans-serif"><br>Faculty of Engineering Technology <br>Department of Biomechanical Engineering<br>7500 AE, The Netherlands<br></span><span style="font-size:5pt;font-family:Calibri,sans-serif"><br></span><span style="font-family:Calibri,sans-serif">Personal: <a href="https://people.utwente.nl/m.sartori"><span style="color:rgb(5,99,193)">https://people.utwente.nl/m.sartori</span></a><br>Lab:<span class="gmail-Apple-converted-space"> </span><a href="https://bit.ly/NMLab"><span style="color:rgb(5,99,193)">https://bit.ly/NMLab</span></a><br>YouTube:<span class="gmail-Apple-converted-space"> </span><a href="https://bit.ly/NMLTube"><span style="color:rgb(5,99,193)">https://bit.ly/NMLTube</span></a></span></p><p class="MsoNormal" style="margin:0cm;font-size:11pt;font-family:Aptos,sans-serif;color:rgb(0,0,0)"><span style="font-family:Calibri,sans-serif"> </span></p><p class="MsoNormal" style="margin:0cm;font-size:11pt;font-family:Aptos,sans-serif;color:rgb(0,0,0)"><span style="font-family:Calibri,sans-serif">!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!</span></p><p class="MsoNormal" style="margin:0cm;font-size:11pt;font-family:Aptos,sans-serif;color:rgb(0,0,0)"><span style="font-family:Calibri,sans-serif">Listen to our<span class="gmail-Apple-converted-space"> </span><a href="https://open.spotify.com/show/3dQjP4kQ9nM3IaD5pHYvxB?si=6d90a5aeb6eb485f"><span style="color:rgb(5,99,193)">podcast</span></a><span class="gmail-Apple-converted-space"> </span>on AI-powered Digital Human Twins!<br>Watch our<span class="gmail-Apple-converted-space"> </span><a href="https://ntr.nl/Focus/287/detail/Geprinte-benen/VPWON_1353472"><span style="color:rgb(5,99,193)">work</span></a><span class="gmail-Apple-converted-space"> </span>on bionic legs featured on Dutch TV!</span></p><p class="MsoNormal" style="margin:0cm;font-size:11pt;font-family:Aptos,sans-serif;color:rgb(0,0,0)"><span style="font-family:Calibri,sans-serif">!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!</span></p></div></div>