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class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div style="text-align:center"><font size="4"><a href="https://www.wwtns.online" target="_blank">https://www.wwtns.online</a><span style="text-align:center"> -</span></font><span style="font-size:large;text-align:center"> on twitter: wwtns@TheoreticalWide</span> </div><div style="text-align:center"><span style="color:rgb(0,0,0);font-family:arial,sans-serif;font-size:large"><br></span></div><div style="text-align:center"><span style="color:rgb(0,0,0);font-family:arial,sans-serif;font-size:large">You are cordially invited to the lecture given by </span><br></div><div style="text-align:center"><span style="color:rgb(0,0,0);font-family:arial,sans-serif;font-size:large"><br></span></div><div style="text-align:center"><p style="background:transparent;border:0px;outline:0px;padding:0px;vertical-align:baseline;font-size:18px;line-height:1.6em;color:rgb(0,0,0);margin:0px"><span style="background:transparent;border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;font-family:helvetica-w01-roman,helvetica-w02-roman,helvetica-lt-w10-roman,sans-serif"><span style="background:transparent;border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline"><span style="background:transparent;border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline">Jonathan Kadmon</span></span></span></p><p style="background:transparent;border:0px;outline:0px;padding:0px;vertical-align:baseline;font-size:18px;line-height:1.6em;color:rgb(0,0,0);margin:0px"><span style="background:transparent;border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;font-family:helvetica-w01-roman,helvetica-w02-roman,helvetica-lt-w10-roman,sans-serif"><span style="background:transparent;border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline"><span style="background:transparent;border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline">The Hebrew University</span></span></span></p></div><div style="text-align:center"><span style="color:rgb(0,0,0);font-family:arial,sans-serif;font-size:large"><br></span></div><div style="text-align:center"><span style="color:rgb(0,0,0);font-size:large">on the topic of </span><span style="color:rgb(0,0,0);font-family:arial,sans-serif;font-size:large"><br></span></div><div style="text-align:center"><span style="color:rgb(0,0,0);font-size:large"><br></span></div><div style="text-align:center"><font color="#000000"><font size="4"><span style="text-align:start">"</span></font><span style="font-family:spinnaker,sans-serif;font-size:20px">Neural mechanisms of adaptive behavior</span><span style="background-color:transparent;font-size:large;text-align:start">"</span></font></div><div style="text-align:center"><font size="4"><font color="#000000"><span style="background-color:transparent"><span style="text-align:start"><br></span></span></font></font></div><div style="text-align:center"><font style="font-size:18px;background-color:transparent">The lecture will be held on zoom on <b>January 31, 2024</b>, at <u><b>11:00 am ET </b></u></font></div><div style="text-align:center"><font style="font-size:18px;background-color:transparent"><u><b><br></b></u></font></div><div style="text-align:center"><font style="font-size:18px;background-color:transparent"><a href="https://streaklinks.com/A9c7PbX_v605iPoFlQDfpvyU/https%3A%2F%2Fu-paris.zoom.us%2Fj%2F87296214746%3Fpwd%3DV3oyZ1JaQUxWVWp1TS9LS0ZiM0xiQT09" style="font-size:small" target="_blank"><font size="4">https://u-paris.zoom.us/j/87296214746?pwd=V3oyZ1JaQUxWVWp1TS9LS0ZiM0xiQT09</font></a> </font><span style="background-color:transparent"> </span><span style="color:rgb(0,0,0);font-family:arial,sans-serif;font-size:large"><br></span></div><div style="text-align:center"><span style="background-color:transparent"><br></span></div><div style="text-align:center"><p style="color:rgb(3,3,3);line-height:1em"><font size="4">Id: 872 9621 4746</font></p><p style="line-height:1em"><font size="4" color="#000000">Passwd: 688274 </font></p><p style="line-height:1em"><font color="#000000"><br></font></p><p style="text-align:left;line-height:1em"><font color="#000000"><font face="verdana, sans-serif"><span style="text-align:justify"><b>Abstract:</b> </span></font></font><span style="background-color:transparent;font-size:15px;letter-spacing:0em;color:rgb(0,0,0)">Animals and humans rapidly adapt their behavior to dynamic environmental changes, such as predator threats or fluctuating food resources, often without immediate rewards. Existing literature posits that animals rely on internal representations of the environment, termed “beliefs”, for their decision policy. However, previous work ties belief updates to external reward signals, which does not explain adaptation in scenarios where trial-and-error approaches are inefficient or potentially perilous. In this work, we propose that the brain utilize dynamic representations that continuously infer the state of the environment, allowing it to update behavior rapidly. I will present a Bayesian theory for state inference in a partially observed Markov Decision Process with multiple interacting latent variables. Optimal behavior requires knowledge of hidden interactions between latent states. I will show that recurrent neural networks trained through reinforcement solve the task by learning the hidden interaction between latent states, and their activity encodes the dynamics of the optimal Bayesian estimators. The behavior of rodents trained on an identical task aligns with our theoretical model and neural network simulations, suggesting that the brain utilizes dynamic internal state representation and inference.</span></p><p style="text-align:left;line-height:1em"><span style="background-color:transparent;font-size:15px;letter-spacing:0em;color:rgb(0,0,0)"><br></span></p><p style="text-align:left;line-height:1em"><i style="background-color:transparent"><font color="#000000"><span style="font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify"><b>About VVTNS :</b> Created as the World Wide Neuroscience Seminar (WWTN</span></font><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify">S) in November 2020 and renamed in homage to Carl van Vreeswijk in Memoriam (April 20, 2022), its aim is to be a platform to exchange ideas among theoreticians. Speakers have the occasion to talk about theoretical aspects of their work which cannot be discussed in a setting where the majority of the audience consists of experimentalists. The seminars, </span></i><i style="background-color:transparent"><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify">held on Wednesdays at 11 am ET,</span></i><i style="background-color:transparent"><span style="color:rgb(0,0,0);font-family:helvetica-w01-light,helvetica-w02-light,sans-serif;text-align:justify"> are 45-50 min long followed by a discussion. The talks are recorded with authorization of the speaker and are available to everybody on our YouTube channel.</span></i></p></div><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div 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</div><br clear="all"><div><br></div><span class="gmail_signature_prefix">-- </span><br><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div>'Life is good ..' (Carl van Vreeswijk, 1962-2022)</div><div>---------------------------------------<br>David Hansel<br>Directeur de Recherche au CNRS</div><div><span style="background-color:rgba(255,255,255,0)">Co-Group leader </span><br>Cerebral Dynamics Plasticity and Learning lab., CNRS<br>45 rue des Saints Peres 75270 Paris Cedex 06<br>Tel (Cell): +33 607508403 - Fax (33).1.49.27.90.62<br></div><div><br></div><div><b style="color:rgb(34,34,34)">CONFIDENTIALITY AND PRIVACY NOTICE:</b><span style="color:rgb(34,34,34)"> </span><i style="color:rgb(34,34,34)">This message and the documents that might be attached, are addressed exclusively to their(s) recipient(s) and may contain privileged or confidential information. The access to this information by people other than those designated is not authorized. If you are not the indicated recipient, you are notified that the use, disclosure and / or copying without authorization is prohibited under current legislation. If you have received this message in error, please kindly inform the sender immediately and proceed to its destruction.</i><br></div><div><br></div></div></div></div></div></div><div hspace="streak-pt-mark" style="max-height:1px"><img alt="" style="width:0px;max-height:0px;overflow:hidden" src="https://mailfoogae.appspot.com/t?sender=aZGhhbnNlbDBAZ21haWwuY29t&type=zerocontent&guid=7d1a0629-0acb-4c3e-941c-d1d2caf43986"><font color="#ffffff" size="1">ᐧ</font></div>