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The FLAG-ERA project NeuronsReunited is looking for a postdoctoral
research associate<br>
(Neuroinformatics/Computational Neuroscience) for a 2 year position
at 0.9 fte.<br>
<br>
Each mental event or voluntary motor act involves the coordinated
activity of neurons in areas of<br>
the brain far apart. Thin, branched and extremely long cellular
processes called axons provide the<br>
physical substrate of these interactions. Since a few years it is
possible to fully trace these long-<br>
range axons one at a time. The goal of the FlagERA research project
"NeuronsReunited" <br>
(<a class="moz-txt-link-freetext" href="https://www.flagera.eu/wp-content/uploads/2020/06/FLAG-ERA_JTC2019_HBP_NeuronsReunited.pdf">https://www.flagera.eu/wp-content/uploads/2020/06/FLAG-ERA_JTC2019_HBP_NeuronsReunited.pdf</a>)<br>
is to create tools for speeding up the conversion of experimental
data into digital axons, and to<br>
precisely place neurons into a digital reference brain to reveal
their context. The tools are applied<br>
to existing and new data in mouse, and the resulting insights are
incorporated into new models for<br>
brain function.<br>
<br>
The project is a collaboration between five international partners,
two experimental partners (Prof.<br>
Francisco Clasca, Madrid; Prof. Egidio d'Angelo, Pavia) and three
computational/theoretical<br>
partners (Prof. Paul Tiesinga, Dr. Rembrandt Bakker, Nijmegen; Prof.
Michele Giugliano, Trieste;<br>
Prof. Sacha Van Albada, Jülich). As a postdoctoral research
associate you will design strategies to<br>
get axonal arbors precisely registered in a brain atlas. The brain
atlas consists of high-resolution<br>
3d dataset that represents the average mouse brain anatomy, while
the neuron consists of a vector<br>
representation of its morphology that can be extended with images of
selected tissue sections.<br>
Depending on your field of expertise, further steps can focus on
automating the process to trace<br>
neurons from stained tissue sections or to integrate the resulting
database of precisely registered<br>
neurons with other data modalities to generate new knowledge. You
will be part of a team that<br>
deals with atlasing and data integration (Nijmegen) and model
building (Jülich, Padova, Trieste).<br>
A key deliverable will be the creation of a gold standard online
catalog of precisely placed<br>
neurons that future generations of neuroscientists can contribute to
and compare data to. The tools<br>
make use of an existing body of work that consists of web-based
applications: <br>
HBP Morphology Viewer
(<a class="moz-txt-link-freetext" href="https://neuroinformatics.nl/HBP/morphology-viewer">https://neuroinformatics.nl/HBP/morphology-viewer</a>), <br>
Scalable Brain Atlas (<a class="moz-txt-link-freetext" href="https://scalablebrainatlas.incf.org/">https://scalablebrainatlas.incf.org/</a>), and
interactive notebooks (Python).<br>
Besides being a member of the project team, you will also be part of
the European Human Brain<br>
Project and have access to the expertise of the large neuroscience
community at the Donders<br>
Institute for Brain, Cognition and Behavior.<br>
<br>
We ask:<br>
• A PhD degree in a quantitative field (engineering, physics,
computational neuroscience,<br>
etc).<br>
• Expertise in neuroscience or interest in acquiring it.<br>
• Excellent programming skills, preferably in JavaScript
applications or Python-based<br>
pipelines.<br>
• Experience with neuroinformatics, visualization/3d-graphics,
image processing, and/or<br>
machine learning.<br>
• Demonstrated ability to work in a multidisciplinary
environment at the forefront of<br>
science.<br>
• Excellent communication skills in spoken and written
English.<br>
<br>
We are:<br>
<br>
The Donders Institute for Brain, Cognition and Behaviour, home to
more than 600 researchers<br>
from 35 countries, is a world-class research centre devoted to
understanding the mechanistic<br>
underpinnings of human cognition and behaviour in health and
disease. The institute's mission<br>
includes conducting excellent interdisciplinary research at the
unique interface between genetic,<br>
molecular and cellular processes at one end and computational,
system-level neuroscience with<br>
cognitive and behavioural analysis at the other end. Within this
playing field, the<br>
Neuroinformatics department plays an essential role in developing
new approaches for both<br>
computational modeling and data processing, all with the aim to turn
raw data into highly valuable<br>
and well-integrated resources from which neuro-scientific insights
can be extracted.<br>
Radboud University<br>
We want to get the best out of science, others and ourselves. Why?
Because this is what the world<br>
around us desperately needs. Leading research and education make an
indispensable contribution<br>
to a healthy, free world with equal opportunities for all. This is
what unites the more than 22,000<br>
students and 5,000 employees at Radboud University. And this
requires even more talent,<br>
collaboration and lifelong learning. You have a part to play!<br>
<br>
We offer:<br>
• Employment: 0.9 FTE.<br>
• A maximum gross monthly salary of € 4,402 based on a 38-hour
working week (salary<br>
scale 10).<br>
• The exact salary depends on the candidate's qualifications
and amount of relevant<br>
professional experience.<br>
• In addition to the salary: an 8% holiday allowance and an
8.3% end-of-year bonus.<br>
• Duration of the contract: 25 months.<br>
• The intended start date is 1 September 2021.<br>
• You will be able to use our Dual Career and Family Care
Services. Our Dual Career and<br>
Family Care Officer can assist you with family-related
support, help your partner or<br>
spouse prepare for the local labour market, provide
customized support in their search for<br>
employment and help your family settle in Nijmegen.<br>
• Have a look at our excellent employment conditions. They
include a good work-life<br>
balance (among other things because of the excellent leave
arrangements), opportunities<br>
for development and a great pension scheme.<br>
<br>
Apply directly<br>
<br>
Please use this link to apply:
<a class="moz-txt-link-freetext" href="https://www.ru.nl/english/working-at/vacature/online">https://www.ru.nl/english/working-at/vacature/online</a>-<br>
solliciteren/?tk=uk&recid=1152432#apply.<br>
Address your application to Paul Tiesinga and submit it no later
than 1 July 2021.<br>
Your application should include the following attachments:<br>
• Letter of motivation.<br>
• CV including contact details of two references.<br>
• Your research statement.<br>
<br>
The first round of interviews will take place on 6th July 2021. The
second round of interviews<br>
will take place on 13th July 2021.<br>
<br>
For more information about this vacancy, please contact:<br>
Paul Tiesinga, Full Professor<br>
Tel.: +31 24 365 22 32<br>
Email: <a class="moz-txt-link-abbreviated" href="mailto:p.tiesinga@science.ru.nl">p.tiesinga@science.ru.nl</a><br>
Rembrandt Bakker, Postdoctoral Researcher<br>
Tel.: +31 24 365 26 33<br>
Email: <a class="moz-txt-link-abbreviated" href="mailto:r.bakker@donders.ru.nl">r.bakker@donders.ru.nl</a><br>
<br>
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