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<p style="margin-top:0in"><strong><i><span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">Scientist – Biological constraints of computation</span></i></strong><o:p></o:p></p>
<p style="margin-top:0in"><span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">Our mission at the Allen Institute is to advance our understanding of how the brain works in health and disease. Using a team science approach, we strive
 to discover how the brain implements fundamental computations through the integration of technological innovation, cutting-edge experiments, modeling, and theory.</span><o:p></o:p></p>
<p style="margin-top:0in;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">The defining aspect of the brain is its capacity to produce behavior. However, how behavior arises from the computations implemented by different systems in the brain, what is the
 set of computations implemented by different systems, and how this set of computations is limited by anatomical constraints remains poorly understood.</span><o:p></o:p></p>
<p style="margin-top:0in;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">We want to use anatomical data (<a href="http://connectivity.brain-map.org/"><span style="color:#003056">http://connectivity.brain-map.org/</span></a>) to constrain the space of
 architectures for the visual system, train models for different etologically relevant tasks, and compare model’s responses with those physiological observed (<a href="https://observatory.brain-map.org/visualcoding"><span style="color:#003056">https://observatory.brain-map.org/visualcoding</span></a>).
 One of the salient characteristics of the responses in the mouse visual system is the large variability of responses to the same images, and the combination of visual and motor responses. We seek to explore the space of tasks which produce similar representations
 to those observed in the mouse brain, with a focus on development of mixed visual/motor representations. The final results of the models trained on etologically relevant tasks can be used as initial states for models learning.</span><o:p></o:p></p>
<p style="margin-top:0in;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">We are seeking a scientist to join the Modeling and Theory team of Stefan Mihalas to help construct <strong><span style="font-family:"Helvetica Neue Light"">biologically constrained
 task driven models</span></strong> <strong><span style="font-family:"Helvetica Neue Light"">of</span></strong> the mouse cortex. The scientist will help transform biological knowledge of structure into architectural constraints, train models with such over
 a range of tasks, and compare the results to in vivo physiology measurements. The scientist is expected to have strong contributions at the level of ideas, and help shape future projects. Our team focuses at extracting principles from large data, integrating
 them in simplified models and using the models to test theories of computation.</span><o:p></o:p></p>
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<strong><span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">Essential Functions</span></strong><o:p></o:p></p>
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<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Construct architectural constraints for the network from large scale connectivity data</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l3 level1 lfo1">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Train models for visual processing with architectural constraints to perform different visual/motor tasks, and compare the results with the physiological recordings</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l3 level1 lfo1">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">In collaboration with experimentalists contribute to the analysis of the anatomical and physiological data</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l3 level1 lfo1">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Contribute scientific ideas based on the modeling results, and help shape future projects</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l3 level1 lfo1">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Develop and maintain computational and associated software tools</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l3 level1 lfo1">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Maintain clear and accurate communication with supervisor and team members</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l3 level1 lfo1">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Publish/present findings in peer-reviewed journals/scientific conferences</span><span style="font-size:11.0pt"><o:p></o:p></span></li></ul>
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<strong><span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">Required Experience and Education</span></strong><o:p></o:p></p>
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<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">PhD degree in computational neuroscience, physics, mathematics, applied mathematics or related field.</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l4 level1 lfo2">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Scientist I: 0-2 years of post-doctoral experience </span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l4 level1 lfo2">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Strong background in scientific computing and data analysis</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l4 level1 lfo2">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Proven ability to code using Python and experience using PyTorch or TensorFLow</span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l4 level1 lfo2">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Strong written and verbal communication skills.</span><span style="font-size:11.0pt"><o:p></o:p></span></li></ul>
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<strong><span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">Preferred Education and Experience </span></strong><o:p></o:p></p>
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<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Experience in computational neuroscience </span><span style="font-size:11.0pt"><o:p></o:p></span></li><li class="MsoNormal" style="color:#003056;mso-margin-bottom-alt:auto;mso-list:l2 level1 lfo3">
<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Ability to meet aggressive timelines and deliverables in a collaborative environment.</span><span style="font-size:11.0pt"><o:p></o:p></span></li></ul>
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<strong><span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">Physical Demands</span></strong><o:p></o:p></p>
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<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">Fine motor movements in fingers/hands to operate computers and other office equipment; lab equipment</span><o:p></o:p></li></ul>
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<strong><span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">Position Type/Expected Hours of Work</span></strong><o:p></o:p></p>
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<span style="font-size:9.0pt;font-family:"Helvetica Neue Light"">This role is currently able to work remotely due to COVID-19 and our focus on employee safety; this may change, and you may be required to work onsite at our South Lake Union office as safety
 restrictions are lifted in relation to COVID-19.</span><o:p></o:p></li></ul>
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<em><span style="font-size:9.0pt;font-family:"Helvetica Neue Light";color:#003056">It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or
 mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state
 or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.</span></em><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt">Apply at: https://alleninstitute.hrmdirect.com/employment/job-opening.php?req=1279097&cust_sort1=29268%2Femployment%2Fjob-openings.php%3Fsearch%3Dtrue&nohd&csrc=37190</span><o:p></o:p></p>
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