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<p style="font-family: "Times New Roman"; font-size: medium">The University of Exeter, UK is looking for a postdoctoral Research Fellow in computational modelling of central pattern generators. This 3-year project in collaboration with neurobiologists from
the University of St Andrews is funded by BBSRC.</p>
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<p style="font-family: "Times New Roman"; font-size: medium">Vertebrate neural circuits are not fixed into producing a single behaviour. They can dynamically change their activity to respond appropriately to changing situations. This project asks how networks
can switch between different behaviours. Specifically, you will investigate the dynamic transition between rhythmic activity patterns in the spinal cord circuits of the tadpole. To do so you will develop reduced and detailed computational models of the tadpole
neural circuits that produce swimming and struggling behaviours.</p>
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<p style="font-family: "Times New Roman"; font-size: medium">You will use reduced models to analyse the dynamic transition between swimming and struggling and determine how coordination among oscillatory circuits changes at the transition. You will also build
detailed models (both anatomical and functional) to determine how the intrinsic characteristics of the neurons and the network properties together produce each behaviour. You will be supported by our experimental collaborators who have determined neuronal
properties and network connectivity with an exquisite level of detail. Predictions from your model simulations will be tested experimentally using an array of electrophysiology and imaging tools.</p>
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<p style="font-family: "Times New Roman"; font-size: medium">The tadpole central pattern generators offer a unique system to ask how vertebrate networks can produce and switch between different behaviours: they are complex enough to generate different behaviours,
but simple enough that we have detailed information to ground our models.</p>
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<p style="font-family: "Times New Roman"; font-size: medium">For more information about this job and to apply, please follow the link https://jobs.exeter.ac.uk and enter keyword 70011</p>
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<p style="font-family: "Times New Roman"; font-size: medium">Enquiries: </p>
<p style="font-family: "Times New Roman"; font-size: medium">Dr Joel Tabak - j.tabak@exeter.ac.uk</p>
<p style="font-family: "Times New Roman"; font-size: medium">Prof Roman Borisyuk - r.m.borisyuk@exeter.ac.uk, r.borisyuk@plymouth.ac.uk</p>
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