Connectionists: Postdoctoral positions in computational and systems biology

[Jagath C Rajapakse (Prof)]

Two postdoctoral positions are available in a project investigating missing and spurious links and labels of molecular networks. The project will begin in January 2017 and is led by Professor Jagath Rajapakse in the School of Computer Science and Engineering, Nanyang Technological University (NTU), Singapore (www.ntu.edu.sg<http://www.ntu.edu.sg/>).

Protein interaction networks (PIN) are widely used in inferring disease mechanisms and in drug discovery. Missing and spurious links and labels of PIN is a challenge and undermine the applications of PIN. The aim of this project is to develop computational techniques and tools for the prediction of missing and spurious links and labels by mapping the hierarchical modularity of protein interaction networks and gene ontology.  Methods will be applied for inferring disease mechanisms in leprosy, psoriasis, and cancer.

Postdoc 1 will research on various models of protein interaction networks and their applications to prioritizing nodes and links, predicting missing and spurious links, and extracting network modules, protein complexes, and biological pathways. A potential candidate will have background and experience machine learning and network analysis.

Postdoc 2: will investigate the hierarchical organization of protein interaction networks and gene ontology, and mapping the two hierarchies to find missing labels in protein interaction networks. The candidate will also research on mapping disease networks to protein interaction networks in order to predict disease related pathways and protein complexes. A potential candidate will have experience in machine learning, ontologies, or text mining.

For postdoctoral positions, PhD in a related field is required. Knowledge of python or R would be an advantage. For more details and applications, please send your curriculum vitae to Professor Jagath Rajapakse (asjagath at ntu.edu.sg<mailto:asjagath at ntu.edu.sg>).



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