<div dir="ltr">Hello All<div><br></div><div>We have recently executed an agreement with the NIH's National Heart Lung and Blood Institute to access some of the largest clinical trials and observational studies in the NHLBI's BioLINCC repository. Access to these cohorts puts us at an equal footing with some of the top medical schools and biostatistics departments in the world.</div><div><br></div><div>We now would be able to frame a design complex epidemiological studies including, but not limited to: </div><div><br></div><div>- Assessment of demographic disparities in cardiovascular health</div><div>- Causal and subgroup identification of heterogeneous benefit to the said interventions.</div><div><br></div><div><div>The availability of these datasets would allow us to answer fundamental questions including: </div><div><br></div><div>- Effect of Lipid Lowering Therapies</div><div>- Effect of Glycemic Control</div><div>- Hypertension Management</div><div>- Optimal Surgical Intervention (CABG/PCI, Delayed or Proactive)</div><div><br></div></div><div>The availability of these data also now gives us the ability of pooling data from multiple studies to create larger cohorts to answer questions that were previously not possible with just a single study.</div><div><br></div><div>The studies also make for good "real world" datasets for generic  machine learning methodology papers.</div><div><br></div><div><b>Our access includes baseline and follow up data from the following studies: </b></div><div><br></div><div><b>ALLHAT</b>:  <a href="https://biolincc.nhlbi.nih.gov/studies/allhat/">https://biolincc.nhlbi.nih.gov/studies/allhat/</a><br><b>ACCORD</b>: <a href="https://biolincc.nhlbi.nih.gov/studies/accord/">https://biolincc.nhlbi.nih.gov/studies/accord/</a></div><div><b>SPRINT</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/sprint/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Systolic Blood Pressure Intervention Trial </a></div><div><b>BARI2D</b>: <a href="https://biolincc.nhlbi.nih.gov/studies/bari2d/">https://biolincc.nhlbi.nih.gov/studies/bari2d/</a></div><div><b>AMIS</b>: <a href="https://biolincc.nhlbi.nih.gov/studies/amis/">https://biolincc.nhlbi.nih.gov/studies/amis/</a><br><b>OAT</b>:  <a href="https://biolincc.nhlbi.nih.gov/studies/oat/">https://biolincc.nhlbi.nih.gov/studies/oat/</a></div><div><b>ROC-CCC</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/roc_ccc/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Resuscitation Outcomes Consortium (ROC) Trial Of Continuous Compressions Versus Standard CPR In Patients With Out-Of-Hospital Cardiac Arrest (CCC)</a></div><div><b>ROC-ALPS</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/roc_alps/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Resuscitation Outcomes Consortium (ROC) Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Ventricular Tachycardia </a></div><div><b>PROMISE</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/promise/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Prospective Multicenter Imaging Study for Evaluation of Chest Pain</a></div><div><b>PEACE</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/peace/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Prevention of Events With Angiotensin-Converting Enzyme Inhibitor Therapy </a></div><div><b>AIMHIGH</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/aimhigh/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes (AIM-HIGH)</a></div><div><b>AMIS</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/amis/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Aspirin-Myocardial Infarction Study </a></div><div><b>BEST</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/best/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Beta-Blocker Evaluation in Survival Trial </a></div><div><b>ENRICHD</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/enrichd/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Enhancing Recovery in Coronary Heart Disease Patients</a></div><div><b>SOLVD</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/solvd/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Studies of Left Ventricular Dysfunction</a></div><div><b>STICH</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/stich/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Surgical Treatment for Ischemic Heart Failure</a></div><div><br><b>Observational Cohorts:</b></div><div><b>ARIC</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/aric/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Atherosclerosis Risk in Communities Study </a></div><div><b>MESA</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/mesa/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Multi-Ethnic Study of Atherosclerosis </a></div><div><b>CARDIA</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/cardia/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(15,105,179);text-decoration-line:none;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Coronary Artery Risk Development in Young Adults</a></div><div><b>SHEP</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/shep/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(35,82,124);outline:0px;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Systolic Hypertension in the Elderly Program </a></div><div><b>SHHS</b>: <a href="https://biolincc.nhlbi.nih.gov/dataset/shhs/" style="box-sizing:border-box;background-color:rgb(245,246,247);color:rgb(35,82,124);outline:0px;font-family:"Helvetica Neue",Helvetica,Arial,sans-serif;font-size:14px">Sleep Heart Health Study </a></div><div><br></div><div><div><b><i>In case any of this is of interest, please reach out. </i></b></div><div><br></div>-- <br><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><span style="color:rgb(0,0,0)"><span style="background-color:rgb(255,255,255)"><span><b>Chirag Nagpal<br></b>
PhD Candidate, Auton Lab<br>
School of Computer Science<br>
Carnegie Mellon University<br></span></span></span></div><div><span style="color:rgb(0,0,0)"><span style="background-color:rgb(255,255,255)"><span><a href="http://cs.cmu.edu/~chiragn" target="_blank">cs.cmu.edu/~chiragn</a><br></span></span></span></div></div></div></div></div></div></div></div>